6KDM

HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:entecavir 5'-triphosphate ternary complex

6KDM の概要

• エントリーDOI: 10.2210/pdb6kdm/pdb
• 分子名称: HIV-1 reverse transcriptase p66 subunit, HIV-1 RT p51 subunit, DNA/RNA (38-MER), ... (7 entities in total)
• 機能のキーワード: entecavir 5'-triphosphate, hiv-1, hbv, reverse transcriptase, drug resistance, drug sensitivity, transferase-dna complex, replication, transferase/dna
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 256874.48

構造登録者

Yasutake, Y.,Hattori, S.I.,Tamura, N.,Maeda, K. (登録日: 2019-07-02, 公開日: 2020-03-04, 最終更新日: 2023-11-22)

• 主引用文献: Yasutake, Y.,Hattori, S.I.,Tamura, N.,Matsuda, K.,Kohgo, S.,Maeda, K.,Mitsuya, H.; Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine.; Sci Rep, 10:3021-3021, 2020; PubMed: 32080249; DOI: 10.1038/s41598-020-59775-w

実験手法

X-RAY DIFFRACTION (2.32 Å)