6KD5
Crystal structure of the extracellular domain of MSPL/TMPRSS13 in complex with dec-RVKR-cmk inhibitor
Summary for 6KD5
Entry DOI | 10.2210/pdb6kd5/pdb |
Descriptor | Transmembrane protease serine 13, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | hydrolase, structural protein-inhibitor complex, structural protein/inhibitor |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 49190.20 |
Authors | Ohno, A.,Maita, N.,Okumura, Y.,Nikawa, T. (deposition date: 2019-06-30, release date: 2020-06-24, Last modification date: 2023-11-22) |
Primary citation | Ohno, A.,Maita, N.,Tabata, T.,Nagano, H.,Arita, K.,Ariyoshi, M.,Uchida, T.,Nakao, R.,Ulla, A.,Sugiura, K.,Kishimoto, K.,Teshima-Kondo, S.,Okumura, Y.,Nikawa, T. Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza. Life Sci Alliance, 4:-, 2021 Cited by PubMed: 33820827DOI: 10.26508/lsa.202000849 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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