6KCS

Crystal structure of HIRAN domain of HLTF in complex with duplex DNA

Summary for 6KCS

• Entry DOI: 10.2210/pdb6kcs/pdb
• Related: 4xzf
• Descriptor: Helicase-like transcription factor, DNA (5'-D(*AP*CP*TP*GP*TP*AP*CP*GP*TP*AP*CP*AP*GP*T)-3') (3 entities in total)
• Functional Keywords: dna complex, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 17630.09

Authors

Hishiki, A.,Hashimoto, A. (deposition date: 2019-06-28, release date: 2020-06-10, Last modification date: 2023-11-22)

• Primary citation: Hishiki, A.,Sato, M.,Hashimoto, H.; Structure of HIRAN domain of human HLTF bound to duplex DNA provides structural basis for DNA unwinding to initiate replication fork regression.; J.Biochem., 167:597-602, 2020; PubMed: 31960921; DOI: 10.1093/jb/mvaa008

Experimental method

X-RAY DIFFRACTION (2.1 Å)