6K35

Crystal structure of GH20 exo beta-N-acetylglucosaminidase from Vibrio harveyi in complex with NAG-thiazoline

Summary for 6K35

• Entry DOI: 10.2210/pdb6k35/pdb
• Related: 6EZR 6EZS 6EZT
• Descriptor: Beta-N-acetylglucosaminidase Nag2, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL (3 entities in total)
• Functional Keywords: anti-bacterial agent, hydrolase
• Biological source: Vibrio harveyi
• Total number of polymer chains: 2
• Total formula weight: 149526.36

Authors

Meekrathok, P.,Stubbs, K.A.,Bulmer, D.M.,van den Berg, B.,Suginta, W. (deposition date: 2019-05-16, release date: 2020-05-13, Last modification date: 2023-11-22)

• Primary citation: Meekrathok, P.,Stubbs, K.A.,Aunkham, A.,Kaewmaneewat, A.,Kardkuntod, A.,Bulmer, D.M.,van den Berg, B.,Suginta, W.; NAG-thiazoline is a potent inhibitor of the Vibrio campbellii GH20 beta-N-Acetylglucosaminidase.; Febs J., 287:4982-4995, 2020; PubMed: 32145141; DOI: 10.1111/febs.15283

Experimental method

X-RAY DIFFRACTION (2.36 Å)