6K28

Crystal structure of the 5-(Hydroxyethyl)-methylthiazole Kinase ThiM from Klebsiella pneumonia in complex with TZE

Summary for 6K28

• Entry DOI: 10.2210/pdb6k28/pdb
• Descriptor: Hydroxyethylthiazole kinase, 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: klebsiella pneumonia, 5-(hydroxyethyl)-methylthiazole kinase, thim, transferase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 3
• Total formula weight: 79096.86

Authors

Chen, Y.,Wang, L.,Shang, F.,Lan, J.,Liu, W.,Xu, Y. (deposition date: 2019-05-13, release date: 2019-07-10, Last modification date: 2024-03-27)

• Primary citation: Chen, Y.,Wang, L.,Shang, F.,Liu, W.,Lan, J.,Chen, J.,Ha, N.C.,Quan, C.,Nam, K.H.,Xu, Y.; Structural insight of the 5-(Hydroxyethyl)-methylthiazole kinase ThiM involving vitamin B1 biosynthetic pathway from the Klebsiella pneumoniae.; Biochem.Biophys.Res.Commun., 518:513-518, 2019; PubMed: 31439375; DOI: 10.1016/j.bbrc.2019.08.086

Experimental method

X-RAY DIFFRACTION (2.002 Å)