6K07

Crystal structure of REV7(R124A) in complex with a Shieldin3 fragment

6K07 の概要

• エントリーDOI: 10.2210/pdb6k07/pdb
• 分子名称: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: dsb repair complex, gene regulation, transcription-protein binding complex, transcription/protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28650.17

構造登録者

Zhang, F.,Dai, Y. (登録日: 2019-05-05, 公開日: 2019-12-11, 最終更新日: 2023-11-22)

• 主引用文献: Dai, Y.,Zhang, F.,Wang, L.,Shan, S.,Gong, Z.,Zhou, Z.; Structural basis for shieldin complex subunit 3-mediated recruitment of the checkpoint protein REV7 during DNA double-strand break repair.; J.Biol.Chem., 295:250-262, 2020; PubMed: 31796627; DOI: 10.1074/jbc.RA119.011464

実験手法

X-RAY DIFFRACTION (2.24 Å)