6JW2

Universal RVD R* accommodates 5hmC via water-mediated interactions

Summary for 6JW2

• Entry DOI: 10.2210/pdb6jw2/pdb
• Descriptor: TAL effector, DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5HC)P*GP*CP*GP*TP*CP*TP*CP*T)-3'), DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), ... (4 entities in total)
• Functional Keywords: methylation tal effector complex, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Xanthomonas campestris pv. armoraciae; More
• Total number of polymer chains: 12
• Total formula weight: 249081.62

Authors

Liu, L.,Yi, C. (deposition date: 2019-04-18, release date: 2020-04-22, Last modification date: 2023-11-22)

• Primary citation: Liu, L.,Zhang, Y.,Liu, M.,Wei, W.,Yi, C.,Peng, J.; Structural Insights into the Specific Recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL Effectors.; J.Mol.Biol., 432:1035-1047, 2020; PubMed: 31863750; DOI: 10.1016/j.jmb.2019.11.023

Experimental method

X-RAY DIFFRACTION (3.03 Å)