6JV5

Crystal structure of 5-methylcytosine containing decamer dsDNA

Summary for 6JV5

• Entry DOI: 10.2210/pdb6jv5/pdb
• Descriptor: DNA (5'-D(*CP*CP*AP*GP*(5CM)P*GP*CP*TP*GP*G)-3') (2 entities in total)
• Functional Keywords: methylation, cytosine, duplex, dna
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 3060.02

Authors

Zhang, L.,Wang, Y.X. (deposition date: 2019-04-15, release date: 2019-07-31, Last modification date: 2024-03-27)

• Primary citation: Fu, T.,Liu, L.,Yang, Q.L.,Wang, Y.,Xu, P.,Zhang, L.,Liu, S.,Dai, Q.,Ji, Q.,Xu, G.L.,He, C.,Luo, C.,Zhang, L.; Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine.; Chem Sci, 10:7407-7417, 2019; PubMed: 31489163; DOI: 10.1039/c9sc02807b

Experimental method

X-RAY DIFFRACTION (1.401 Å)