6JTB

Crystal structure of dipeptidyl peptidase 11 (DPP11) with citrate from Porphyromonas gingivalis (Space)

Summary for 6JTB

Entry DOI	10.2210/pdb6jtb/pdb
Related	4Y04
Descriptor	Asp/Glu-specific dipeptidyl-peptidase, DI(HYDROXYETHYL)ETHER, CITRIC ACID, ... (6 entities in total)
Functional Keywords	dipeptidyl aminopeptidase, s46, perio, microgravity, antimicrobial, hydrolase
Biological source	Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / CIP 103683 / JCM 12257 / NCTC 11834 / 2561)
Total number of polymer chains	1
Total formula weight	83175.27
Authors	Sakamoto, Y.,Suzuki, Y.,Iizuka, I.,Roppongi, S.,Kushibiki, C.,Nakamura, A.,Ogasawara, W.,Tanaka, N. (deposition date: 2019-04-10, release date: 2019-10-02, Last modification date: 2023-11-22)
Primary citation	Sakamoto, Y.,Suzuki, Y.,Nakamura, A.,Watanabe, Y.,Sekiya, M.,Roppongi, S.,Kushibiki, C.,Iizuka, I.,Tani, O.,Sakashita, H.,Inaka, K.,Tanaka, H.,Yamada, M.,Ohta, K.,Honma, N.,Shida, Y.,Ogasawara, W.,Nakanishi-Matsui, M.,Nonaka, T.,Gouda, H.,Tanaka, N. Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase. Sci Rep, 9:13587-13587, 2019 Cited by PubMed: 31537874 DOI: 10.1038/s41598-019-49984-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation