6JT0

Structure of human soluble guanylate cyclase in the unliganded state

Summary for 6JT0

• Entry DOI: 10.2210/pdb6jt0/pdb
• EMDB information: 9883
• Descriptor: Guanylate cyclase soluble subunit alpha-1, Guanylate cyclase soluble subunit beta-1, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• Functional Keywords: soluble guanylate cyclase, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 148782.29

Authors

Chen, L.,Kang, Y.,Liu, R.,Wu, J.-X. (deposition date: 2019-04-08, release date: 2019-08-28, Last modification date: 2024-03-27)

• Primary citation: Kang, Y.,Liu, R.,Wu, J.X.,Chen, L.; Structural insights into the mechanism of human soluble guanylate cyclase.; Nature, 574:206-210, 2019; PubMed: 31514202; DOI: 10.1038/s41586-019-1584-6

Experimental method

ELECTRON MICROSCOPY (4 Å)