6JP7

Human antibody 32D6 Fab in complex with PEG

6JP7 の概要

• エントリーDOI: 10.2210/pdb6jp7/pdb
• 分子名称: immunoglobulin Fab heavy chain, immunoglobulin Fab light chain, HEXAETHYLENE GLYCOL, ... (5 entities in total)
• 機能のキーワード: antibody fab, influenza hemagglutinin, complex structure, specific binding, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49603.19

構造登録者

Lee, C.C.,Ko, T.P.,Lin, L.L.,Wang, A.H.J. (登録日: 2019-03-26, 公開日: 2020-02-05, 最終更新日: 2024-11-06)

主引用文献

Lee, C.C.,Su, Y.C.,Ko, T.P.,Lin, L.L.,Yang, C.Y.,Chang, S.S.,Roffler, S.R.,Wang, A.H.
Structural basis of polyethylene glycol recognition by antibody.
J.Biomed.Sci., 27:12-12, 2020

PubMed Abstract: Polyethylene glycol (PEG) is widely used in industry and medicine. Anti-PEG antibodies have been developed for characterizing PEGylated drugs and other applications. However, the underlying mechanism for specific PEG binding has not been elucidated.

PubMed: 31907057
DOI: 10.1186/s12929-019-0589-7

実験手法

X-RAY DIFFRACTION (1.909 Å)