Summary for 6JNO
| Entry DOI | 10.2210/pdb6jno/pdb |
| Descriptor | Retinoic acid receptor RXR-alpha, 7-oxidanyl-2-oxidanylidene-6-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)chromene-3-carboxylic acid (3 entities in total) |
| Functional Keywords | retinoid x receptor alpha, ligand binding domain, fluorescent reagent, inactive form, transcription |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 108903.64 |
| Authors | Kawasaki, M.,Nakano, S.,Motoyama, T.,Yamada, S.,Watanabe, M.,Takamura, Y.,Fujihara, M.,Tokiwa, H.,Kakuta, H.,Ito, S. (deposition date: 2019-03-17, release date: 2019-11-20, Last modification date: 2023-11-22) |
| Primary citation | Yamada, S.,Kawasaki, M.,Fujihara, M.,Watanabe, M.,Takamura, Y.,Takioku, M.,Nishioka, H.,Takeuchi, Y.,Makishima, M.,Motoyama, T.,Ito, S.,Tokiwa, H.,Nakano, S.,Kakuta, H. Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening. J.Med.Chem., 62:8809-8818, 2019 Cited by PubMed: 31483660DOI: 10.1021/acs.jmedchem.9b00995 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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