6JLV

Near-Atomic Resolution Structure of the CYP102A1 Haem Domain with N-Abietoyl-L-Tryptophan

6JLV の概要

• エントリーDOI: 10.2210/pdb6jlv/pdb
• 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, (2S)-2-[[(1R,4aR,4bR,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,4b,5,6,10,10a-octahydrophenanthren-1-yl]carbonylamino]-3-( 1H-indol-3-yl)propanoic acid, ... (7 entities in total)
• 機能のキーワード: monooxygenase, oxidoreductase
• 由来する生物種: Bacillus megaterium
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 108922.09

構造登録者

Stanfield, J.K.,Kasai, C.,Sugimoto, H.,Shiro, Y.,Watanabe, Y.,Shoji, O. (登録日: 2019-03-07, 公開日: 2020-03-18, 最終更新日: 2023-11-22)

• 主引用文献: Stanfield, J.K.,Omura, K.,Matsumoto, A.,Kasai, C.,Sugimoto, H.,Shiro, Y.,Watanabe, Y.,Shoji, O.; Crystals in Minutes: Instant On-Site Microcrystallisation of Various Flavours of the CYP102A1 (P450BM3) Haem Domain.; Angew.Chem.Int.Ed.Engl., 59:7611-7618, 2020; PubMed: 32157795; DOI: 10.1002/anie.201913407

実験手法

X-RAY DIFFRACTION (1.22 Å)