6JKA
Crystal structure of metallo-beta-lactamse, IMP-1, in complex with a thiazole-bearing inhibitor
Summary for 6JKA
Entry DOI | 10.2210/pdb6jka/pdb |
Descriptor | Metallo-beta-lactamase type 2, ZINC ION, 6-[2-(phenoxymethyl)-1,3-thiazol-4-yl]-3,4-dihydro-1H-quinolin-2-one, ... (5 entities in total) |
Functional Keywords | hydrolase |
Biological source | Serratia marcescens |
Total number of polymer chains | 4 |
Total formula weight | 101612.60 |
Authors | Kamo, T.,Kuroda, K.,Kondo, S.,Hayashi, U.,Fudo, S.,Nukaga, M.,Hoshino, T. (deposition date: 2019-02-28, release date: 2020-03-25, Last modification date: 2023-11-22) |
Primary citation | Kamo, T.,Kuroda, K.,Kondo, S.,Hayashi, U.,Fudo, S.,Yoneda, T.,Takaya, A.,Nukaga, M.,Hoshino, T. Identification of the Inhibitory Compounds for Metallo-beta-lactamases and Structural Analysis of the Binding Modes. Chem Pharm Bull (Tokyo), 69:1179-1183, 2021 Cited by PubMed: 34853284DOI: 10.1248/cpb.c21-00611 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.006 Å) |
Structure validation
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