6JFL

Nucleotide-free Mitofusin2 (MFN2)

Summary for 6JFL

Entry DOI	10.2210/pdb6jfl/pdb
Descriptor	Mitofusin-2,cDNA FLJ57997, highly similar to Transmembrane GTPase MFN2, GLYCEROL, CALCIUM ION, ... (4 entities in total)
Functional Keywords	mitochondriral fusion, gtpase activity, cmt2a, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	199454.26
Authors	Li, Y.J.,Cao, Y.L.,Feng, J.X.,Qi, Y.B.,Meng, S.X.,Yang, J.F.,Zhong, Y.T.,Kang, S.S.,Chen, X.X.,Lan, L.,Luo, L.,Yu, B.,Chen, S.D.,Chan, D.C.,Hu, J.J.,Gao, S. (deposition date: 2019-02-10, release date: 2019-11-13, Last modification date: 2023-11-22)
Primary citation	Li, Y.J.,Cao, Y.L.,Feng, J.X.,Qi, Y.,Meng, S.,Yang, J.F.,Zhong, Y.T.,Kang, S.,Chen, X.,Lan, L.,Luo, L.,Yu, B.,Chen, S.,Chan, D.C.,Hu, J.,Gao, S. Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset. Nat Commun, 10:4914-4914, 2019 Cited by PubMed: 31664033 DOI: 10.1038/s41467-019-12912-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.806 Å)

Structure validation