6JD7

Crystal structure of anti-CRISPR protein AcrIIC2 dimer

Summary for 6JD7

Entry DOI	10.2210/pdb6jd7/pdb
Descriptor	AcrIIC2, MAGNESIUM ION, ACETATE ION, ... (4 entities in total)
Functional Keywords	crispr-cas9, nme1cas9, nmecas9, anti-crispr, acriic2, hydrolase inhibitor
Biological source	Neisseria meningitidis 8013
Total number of polymer chains	3
Total formula weight	42673.84
Authors	Cheng, Z.,Huang, X.,Sun, W.,Wang, Y.L. (deposition date: 2019-01-31, release date: 2019-05-15, Last modification date: 2024-03-27)
Primary citation	Thavalingam, A.,Cheng, Z.,Garcia, B.,Huang, X.,Shah, M.,Sun, W.,Wang, M.,Harrington, L.,Hwang, S.,Hidalgo-Reyes, Y.,Sontheimer, E.J.,Doudna, J.,Davidson, A.R.,Moraes, T.F.,Wang, Y.,Maxwell, K.L. Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2. Nat Commun, 10:2806-2806, 2019 Cited by PubMed: 31243272 DOI: 10.1038/s41467-019-10577-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.45 Å)

Structure validation