6JCW
Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) with Mg2+ at pH8.5
Summary for 6JCW
Entry DOI | 10.2210/pdb6jcw/pdb |
EMDB information | 9799 |
Descriptor | ketol-acid reductoisomerase, MAGNESIUM ION (3 entities in total) |
Functional Keywords | bi-specific, thermostable, reductoisomerase, magnesium-dependent, dodecamer, knotted protein, isomerase |
Biological source | Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) |
Total number of polymer chains | 12 |
Total formula weight | 447341.58 |
Authors | Chen, C.Y.,Chang, Y.C.,Lin, K.F.,Huang, C.H.,Lin, B.L.,Ko, T.P.,Hsieh, D.L.,Tsai, M.D. (deposition date: 2019-01-30, release date: 2019-04-17, Last modification date: 2024-03-27) |
Primary citation | Chen, C.Y.,Chang, Y.C.,Lin, B.L.,Lin, K.F.,Huang, C.H.,Hsieh, D.L.,Ko, T.P.,Tsai, M.D. Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase. J. Am. Chem. Soc., 141:6136-6140, 2019 Cited by PubMed: 30921515DOI: 10.1021/jacs.9b01354 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.04 Å) |
Structure validation
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