6JCO

Crystal structure of calcium free human gelsolin amyloid mutant D187N

Summary for 6JCO

Entry DOI	10.2210/pdb6jco/pdb
Descriptor	Gelsolin (1 entity in total)
Functional Keywords	gelsolin, amyloidosis, calcium activation, actin binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	160551.80
Authors	Zorgati, H.,Robinson, R.C. (deposition date: 2019-01-29, release date: 2019-06-12, Last modification date: 2023-11-22)
Primary citation	Zorgati, H.,Larsson, M.,Ren, W.,Sim, A.Y.L.,Gettemans, J.,Grimes, J.M.,Li, W.,Robinson, R.C. The role of gelsolin domain 3 in familial amyloidosis (Finnish type). Proc.Natl.Acad.Sci.USA, 116:13958-13963, 2019 Cited by PubMed: 31243148 DOI: 10.1073/pnas.1902189116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.88 Å)

Structure validation