6JCJ
Structure of crolibulin in complex with tubulin
Summary for 6JCJ
Entry DOI | 10.2210/pdb6jcj/pdb |
Descriptor | Tubulin alpha-1B chain, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Tubulin beta-2B chain, ... (11 entities in total) |
Functional Keywords | cbsis, colchicine binding site inhibitors, cell cycle |
Biological source | Sus scrofa (Pig) More |
Total number of polymer chains | 6 |
Total formula weight | 264810.51 |
Authors | |
Primary citation | Zhang, Z.,Wang, C.,Ma, L.,Jiang, X.,Wu, C.,Wang, Y.,Jiang, Y.,Zheng, W.,Yang, Y.,Ma, Y.,Yang, J. Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design. Biochem. Biophys. Res. Commun., 511:381-386, 2019 Cited by PubMed: 30803758DOI: 10.1016/j.bbrc.2019.02.064 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report