6JB1

Structure of pancreatic ATP-sensitive potassium channel bound with repaglinide and ATPgammaS at 3.3A resolution

Summary for 6JB1

• Entry DOI: 10.2210/pdb6jb1/pdb
• EMDB information: 6832 9787
• Descriptor: ATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8 isoform X2, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ... (7 entities in total)
• Functional Keywords: katp, channel, repaglinide, kir, abc transporter, sur, membrane protein, diabetes, insulin secretagogue
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 8
• Total formula weight: 933665.93

Authors

Chen, L.,Ding, D.,Wang, M.,Wu, J.-X.,Kang, Y. (deposition date: 2019-01-25, release date: 2019-05-22, Last modification date: 2021-09-29)

• Primary citation: Ding, D.,Wang, M.,Wu, J.X.,Kang, Y.,Chen, L.; The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.; Cell Rep, 27:1848-1857.e4, 2019; PubMed: 31067468; DOI: 10.1016/j.celrep.2019.04.050

Experimental method

ELECTRON MICROSCOPY (3.3 Å)