6JB1

Structure of pancreatic ATP-sensitive potassium channel bound with repaglinide and ATPgammaS at 3.3A resolution

6JB1 の概要

• エントリーDOI: 10.2210/pdb6jb1/pdb
• EMDBエントリー: 6832 9787
• 分子名称: ATP-sensitive inward rectifier potassium channel 11, ATP-binding cassette sub-family C member 8 isoform X2, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ... (7 entities in total)
• 機能のキーワード: katp, channel, repaglinide, kir, abc transporter, sur, membrane protein, diabetes, insulin secretagogue
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 933665.93

構造登録者

Chen, L.,Ding, D.,Wang, M.,Wu, J.-X.,Kang, Y. (登録日: 2019-01-25, 公開日: 2019-05-22, 最終更新日: 2021-09-29)

• 主引用文献: Ding, D.,Wang, M.,Wu, J.X.,Kang, Y.,Chen, L.; The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.; Cell Rep, 27:1848-1857.e4, 2019; PubMed: 31067468; DOI: 10.1016/j.celrep.2019.04.050

実験手法

ELECTRON MICROSCOPY (3.3 Å)