Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with a napthalimide derivative

Summary for 6JAW

DescriptorGroup II chitinase, 2-[3-(morpholin-4-yl)propyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, N-ACETYL-D-GLUCOSAMINE, ... (4 entities in total)
Functional Keywordsinhibitor complex, chitinase, hydrolase
Biological sourceOstrinia furnacalis (Asian corn borer)
Total number of polymer chains1
Total molecular weight45013.98
Chen, W.,Zhou, Y.,Yang, Q. (deposition date: 2019-01-25, release date: 2019-05-15)
Primary citation
Chen, W.,Zhou, Y.,Yang, Q.
Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.
J.Biol.Chem., 2019
PubMed: 31053640 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.RA119.007812
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1893 0.3% 0.9% 8.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6jaw
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Molmil generated image of 6jaw
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