6J6Y
FGFR4 D2 - Fab complex
Summary for 6J6Y
Entry DOI | 10.2210/pdb6j6y/pdb |
Descriptor | Fibroblast growth factor receptor 4, Fab Heavy chain, Fab light chain, ... (4 entities in total) |
Functional Keywords | fab, transferase-immune system complex, transferase/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 128466.55 |
Authors | Takahashi, M.,Hanzawa, H. (deposition date: 2019-01-16, release date: 2019-08-07, Last modification date: 2019-10-16) |
Primary citation | Bartz, R.,Fukuchi, K.,Ohtsuka, T.,Lange, T.,Gruner, K.,Watanabe, I.,Hayashi, S.,Oda, Y.,Kawaida, R.,Komori, H.,Kashimoto, Y.,Wirtz, P.,Mayer, J.A.,Redondo-Muller, M.,Saito, S.,Takahashi, M.,Hanzawa, H.,Imai, E.,Martinez, A.,Hanai, M.,Haussinger, D.,Chapman, R.W.,Agatsuma, T.,Bange, J.,Abraham, R. Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity. Mol.Cancer Ther., 18:1832-1843, 2019 Cited by PubMed: 31350344DOI: 10.1158/1535-7163.MCT-18-0048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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