6J3C
Crystal structure of human DHODH in complex with inhibitor 1291
6J3C の概要
エントリーDOI | 10.2210/pdb6j3c/pdb |
分子名称 | Dihydroorotate dehydrogenase (quinone), mitochondrial, SULFATE ION, FLAVIN MONONUCLEOTIDE, ... (7 entities in total) |
機能のキーワード | dhodh, inhibitor, complex, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
由来する生物種 | Homo sapiens (Human) |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 41361.90 |
構造登録者 | |
主引用文献 | Zeng, T.,Zuo, Z.,Luo, Y.,Zhao, Y.,Yu, Y.,Chen, Q. A novel series of human dihydroorotate dehydrogenase inhibitors discovered by in vitro screening: inhibition activity and crystallographic binding mode. Febs Open Bio, 9:1348-1354, 2019 Cited by PubMed: 31087527DOI: 10.1002/2211-5463.12658 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.851 Å) |
構造検証レポート
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