6J26

Crystal structure of the branched-chain polyamine synthase from Thermococcus kodakarensis (Tk-BpsA) in complex with N4-bis(aminopropyl)spermidine and 5'-methylthioadenosine

6J26 の概要

• エントリーDOI: 10.2210/pdb6j26/pdb
• 分子名称: N(4)-bis(aminopropyl)spermidine synthase, 5'-DEOXY-5'-METHYLTHIOADENOSINE, N~1~,N~1~,N~1~-tris(3-azaniumylpropyl)butane-1,4-diaminium, ... (5 entities in total)
• 機能のキーワード: n(4)-bis(aminopropyl)spermidine synthase, polyamine biosynthesis, spermidine, branched polyamines, transferase
• 由来する生物種: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 86071.34

構造登録者

Mizohata, E.,Toyoda, M.,Fujita, J.,Inoue, T. (登録日: 2018-12-31, 公開日: 2019-06-26, 最終更新日: 2023-11-22)

• 主引用文献: Hidese, R.,Toyoda, M.,Yoshino, K.I.,Fukuda, W.,Wihardja, G.A.,Kimura, S.,Fujita, J.,Niitsu, M.,Oshima, T.,Imanaka, T.,Mizohata, E.,Fujiwara, S.; The C-terminal flexible region of branched-chain polyamine synthase facilitates substrate specificity and catalysis.; Febs J., 286:3926-3940, 2019; PubMed: 31162806; DOI: 10.1111/febs.14949

実験手法

X-RAY DIFFRACTION (2 Å)