6J1N

Anisodus acutangulus type III polyketide sythase AaPKS2 in complex with 4-carboxy-3-oxobutanoyl-CoA

6J1N の概要

• エントリーDOI: 10.2210/pdb6j1n/pdb
• 分子名称: A. acutangulus PKS2, (3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,19,21-tetraoxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide (non-preferred name) (3 entities in total)
• 機能のキーワード: anisodus acutangulus, type iii polyketide sythase, tropane alkaloids biosynthesis, biosynthetic protein
• 由来する生物種: Anisodus acutangulus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 95244.94

構造登録者

Fang, C.L.,Zhang, Y. (登録日: 2018-12-28, 公開日: 2019-09-11, 最終更新日: 2023-11-22)

• 主引用文献: Huang, J.P.,Fang, C.,Ma, X.,Wang, L.,Yang, J.,Luo, J.,Yan, Y.,Zhang, Y.,Huang, S.X.; Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation.; Nat Commun, 10:4036-4036, 2019; PubMed: 31492848; DOI: 10.1038/s41467-019-11987-z

実験手法

X-RAY DIFFRACTION (2.532 Å)