6J0O

Crystal structure of CERT START domain in complex with compound SC1

Summary for 6J0O

• Entry DOI: 10.2210/pdb6j0o/pdb
• Related: 5ZYG 5ZYH 5ZYI 5ZYJ 5ZYK 5ZYL 5ZYM 6IEZ 6IF0
• Descriptor: LIPID-TRANSFER PROTEIN CERT, 2-[4-[2-fluoranyl-5-[3-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]phenyl]phenyl]sulfonylethanol, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: cert, ph, start, complex, lipid transport
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 27494.27

Authors

Suzuki, M.,Nakao, N.,Ueno, M.,Sakai, S.,Egawa, D.,Hanzawa, H.,Kawasaki, S.,Kumagai, K.,Kobayashi, S.,Hanada, K. (deposition date: 2018-12-25, release date: 2019-02-27, Last modification date: 2024-03-27)

• Primary citation: Nakao, N.,Ueno, M.,Sakai, S.,Egawa, D.,Hanzawa, H.,Kawasaki, S.,Kumagai, K.,Suzuki, M.,Kobayashi, S.,Hanada, K.; Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT; Commun Chem, 2019; DOI: 10.1038/s42004-019-0118-3

Experimental method

X-RAY DIFFRACTION (1.8 Å)