6IYC

Recognition of the Amyloid Precursor Protein by Human gamma-secretase

Summary for 6IYC

• Entry DOI: 10.2210/pdb6iyc/pdb
• EMDB information: 9751
• Descriptor: Nicastrin, CHOLESTEROL, Presenilin-1, ... (10 entities in total)
• Functional Keywords: complex, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 191217.04

Authors

Zhou, R.,Yang, G.,Guo, X.,Zhou, Q.,Lei, J.,Shi, Y. (deposition date: 2018-12-14, release date: 2019-01-23, Last modification date: 2020-07-29)

• Primary citation: Zhou, R.,Yang, G.,Guo, X.,Zhou, Q.,Lei, J.,Shi, Y.; Recognition of the amyloid precursor protein by human gamma-secretase.; Science, 363:-, 2019; PubMed: 30630874; DOI: 10.1126/science.aaw0930

Experimental method

ELECTRON MICROSCOPY (2.6 Å)