6IX5

The structure of LepI complex with SAM and its substrate analogue

6IX5 の概要

• エントリーDOI: 10.2210/pdb6ix5/pdb
• 分子名称: O-methyltransferase lepI, S-ADENOSYLMETHIONINE, 4-hydroxy-3-[(2S,6E,8E)-2-methyldeca-6,8-dienoyl]-5-phenylpyridin-2(1H)-one, ... (9 entities in total)
• 機能のキーワード: leporin, sam, o-methyltransferase, pericyclase, biosynthetic protein
• 由来する生物種: Aspergillus flavus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 93967.00

構造登録者

Cai, Y.,Ohashi, M.,Hai, Y.,Tang, Y.,Zhou, J. (登録日: 2018-12-09, 公開日: 2019-07-17, 最終更新日: 2023-11-22)

• 主引用文献: Cai, Y.,Hai, Y.,Ohashi, M.,Jamieson, C.S.,Garcia-Borras, M.,Houk, K.N.,Zhou, J.,Tang, Y.; Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI.; Nat.Chem., 11:812-820, 2019; PubMed: 31332284; DOI: 10.1038/s41557-019-0294-x

実験手法

X-RAY DIFFRACTION (1.7 Å)