6IX3

The structure of LepI complex with SAM

Summary for 6IX3

DescriptorO-methyltransferase lepI, S-ADENOSYLMETHIONINE, CHLORIDE ION, ... (4 entities in total)
Functional Keywordsleporin, sam, o-methyltransferase, pericyclase, biosynthetic protein
Biological sourceAspergillus flavus
Total number of polymer chains2
Total molecular weight91815.7
Authors
Cai, Y.,Ohashi, M.,Hai, Y.,Tang, Y.,Zhou, J. (deposition date: 2018-12-09, release date: 2019-07-17, Last modification date: 2019-08-07)
Primary citation
Cai, Y.,Hai, Y.,Ohashi, M.,Jamieson, C.S.,Garcia-Borras, M.,Houk, K.N.,Zhou, J.,Tang, Y.
Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI.
Nat.Chem., 2019
PubMed: 31332284 (PDB entries with the same primary citation)
DOI: 10.1038/s41557-019-0294-x
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.13 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.18170 2.3% 1.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution