6IW5

Crystal structure of YFV-China sE in prefusion state

Summary for 6IW5

DescriptorEnvelope protein (2 entities in total)
Functional Keywordsyellow fever virus, neutralizing monoclonal antibody, envelope protein, flavivirus, viral protein
Biological sourceYellow fever virus
Total number of polymer chains4
Total molecular weight171105.16
Authors
Lu, X.S.,Xiao, H.X.,Li, S.H.,Pang, X.F. (deposition date: 2018-12-04, release date: 2019-02-13)
Primary citation
Lu, X.,Xiao, H.,Li, S.,Pang, X.,Song, J.,Liu, S.,Cheng, H.,Li, Y.,Wang, X.,Huang, C.,Guo, T.,Ter Meulen, J.,Daffis, S.,Yan, J.,Dai, L.,Rao, Z.,Klenk, H.D.,Qi, J.,Shi, Y.,Gao, G.F.
Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26:438-446.e5, 2019
PubMed: 30625326 (PDB entries with the same primary citation)
DOI: 10.1016/j.celrep.2018.12.065
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.29113 2.0% 2.0% 6.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6iw5
no rotation
Molmil generated image of 6iw5
rotated about x axis by 90°
Molmil generated image of 6iw5
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 6iw5
no rotation
Molmil generated image of 6iw5
rotated about x axis by 90°
Molmil generated image of 6iw5
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6iw5.pdb2.gz [244.89 KB])
Coordinate files for Biological unit (6iw5.pdb1.gz [250.68 KB])