6IW2
Crystal structure of 5A ScFv in complex with YFV-17D sE in prefusion state
Summary for 6IW2
Entry DOI | 10.2210/pdb6iw2/pdb |
Descriptor | Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A (3 entities in total) |
Functional Keywords | yellow fever virus, neutralizing monoclonal antibody, envelope protein, flavivirus, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Yellow fever virus (strain 17D vaccine) (YFV) More |
Total number of polymer chains | 18 |
Total formula weight | 410867.59 |
Authors | |
Primary citation | Lu, X.,Xiao, H.,Li, S.,Pang, X.,Song, J.,Liu, S.,Cheng, H.,Li, Y.,Wang, X.,Huang, C.,Guo, T.,Ter Meulen, J.,Daffis, S.,Yan, J.,Dai, L.,Rao, Z.,Klenk, H.D.,Qi, J.,Shi, Y.,Gao, G.F. Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope. Cell Rep, 26:438-446.e5, 2019 Cited by PubMed: 30625326DOI: 10.1016/j.celrep.2018.12.065 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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