6IUV

Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 3C11

6IUV の概要

• エントリーDOI: 10.2210/pdb6iuv/pdb
• 分子名称: Hemagglutinin, 3C11 Light Chain, 3C11 Heavy Chain, ... (5 entities in total)
• 機能のキーワード: influenza virus, hpai, h5n1, neutralizing antibody, epitope, major vulnerable site, vaccine development, immune system
• 由来する生物種: Influenza A virus (A/Hong Kong/482/97(H5N1)) (A/Hong Kong/482/97(H5N1)); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 149036.50

構造登録者

Wang, P.,Zuo, Y.,Sun, J.,Zhang, L.,Wang, X. (登録日: 2018-11-30, 公開日: 2019-01-16, 最終更新日: 2023-11-22)

• 主引用文献: Wang, P.,Zuo, Y.,Sun, J.,Zuo, T.,Zhang, S.,Guo, S.,Shi, X.,Liang, M.,Zhou, P.,Zhang, L.,Wang, X.; Structural and functional definition of a vulnerable site on the hemagglutinin of highly pathogenic avian influenza A virus H5N1.; J. Biol. Chem., 294:4290-4303, 2019; PubMed: 30737282; DOI: 10.1074/jbc.RA118.007008

実験手法

X-RAY DIFFRACTION (2.332 Å)