6ITU

Crystal Structure of the GULP1 PTB domain-APP peptide complex

Summary for 6ITU

• Entry DOI: 10.2210/pdb6itu/pdb
• Descriptor: PTB domain-containing engulfment adapter protein 1, Amyloid beta A4 protein, SULFATE ION, ... (5 entities in total)
• Functional Keywords: ptb, app-binding, phosphoprotein, cytoplasmic, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 21198.25

Authors

Yung, K.W.Y.,Lau, K.F.,Ngo, J.C.K. (deposition date: 2018-11-26, release date: 2019-08-14, Last modification date: 2023-11-22)

• Primary citation: Chau, D.D.,Yung, K.W.,Chan, W.W.,An, Y.,Hao, Y.,Chan, H.E.,Ngo, J.C.,Lau, K.F.; Attenuation of amyloid-beta generation by atypical protein kinase C-mediated phosphorylation of engulfment adaptor PTB domain containing 1 threonine 35.; Faseb J., 33:12019-12035, 2019; PubMed: 31373844; DOI: 10.1096/fj.201802825RR

Experimental method

X-RAY DIFFRACTION (2.17 Å)