6ITQ

Crystal structure of cortisol complexed with its nanobody at pH 10.5

6ITQ の概要

• エントリーDOI: 10.2210/pdb6itq/pdb
• 分子名称: anti-cortisol camelid antibody, (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: cortisol, complex, nanobody, camelid antibody, immune system
• 由来する生物種: Camelus bactrianus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 56762.35

構造登録者

Ding, Y.,Ding, L.L.,Wang, Z.Y.,Zhong, P.Y. (登録日: 2018-11-24, 公開日: 2019-07-24, 最終更新日: 2023-11-22)

• 主引用文献: Ding, L.,Wang, Z.,Zhong, P.,Jiang, H.,Zhao, Z.,Zhang, Y.,Ren, Z.,Ding, Y.; Structural insights into the mechanism of single domain VHH antibody binding to cortisol.; Febs Lett., 593:1248-1256, 2019; PubMed: 31049949; DOI: 10.1002/1873-3468.13398

実験手法

X-RAY DIFFRACTION (1.526 Å)