6ISR

structure of lipase mutant with Cys-His-Asp catalytic triad

Summary for 6ISR

• Entry DOI: 10.2210/pdb6isr/pdb
• Descriptor: Lipase B, NICKEL (II) ION, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• Functional Keywords: calb, hydrolase
• Biological source: Pseudozyma antarctica (Yeast)
• Total number of polymer chains: 2
• Total formula weight: 67707.67

Authors

Cen, Y.X.,Zhou, J.H.,Wu, Q. (deposition date: 2018-11-18, release date: 2019-07-24, Last modification date: 2023-11-22)

• Primary citation: Cen, Y.,Singh, W.,Arkin, M.,Moody, T.S.,Huang, M.,Zhou, J.,Wu, Q.,Reetz, M.T.; Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.; Nat Commun, 10:3198-3198, 2019; PubMed: 31324776; DOI: 10.1038/s41467-019-11155-3

Experimental method

X-RAY DIFFRACTION (2.6 Å)