6ISD

Crystal structure of Arabidopsis thaliana HPPD complexed with sulcotrione

「5DHW」から置き換えられました

6ISD の概要

• エントリーDOI: 10.2210/pdb6isd/pdb
• 分子名称: 4-hydroxyphenylpyruvate dioxygenase, 2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione, COBALT (II) ION, ... (4 entities in total)
• 機能のキーワード: 4-hydroxyphenylpyruvate dioxygenase, slow binding inhibitors, drug design, oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• 由来する生物種: Arabidopsis thaliana (Mouse-ear cress)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 98523.07

構造登録者

Yang, W.C.,Yang, G.F. (登録日: 2018-11-16, 公開日: 2018-11-28, 最終更新日: 2023-11-22)

• 主引用文献: Lin, H.Y.,Yang, J.F.,Wang, D.W.,Hao, G.F.,Dong, J.Q.,Wang, Y.X.,Yang, W.C.,Wu, J.W.,Zhan, C.G.,Yang, G.F.; Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations.; FEBS J., 286:975-990, 2019; PubMed: 30632699; DOI: 10.1111/febs.14747

実験手法

X-RAY DIFFRACTION (2.4 Å)