6IRR

Solution structure of DISC1/ATF4 complex

6IRR の概要

• エントリーDOI: 10.2210/pdb6irr/pdb
• 分子名称: Disrupted in schizophrenia 1 homolog,Cyclic AMP-dependent transcription factor ATF-4 (1 entity in total)
• 機能のキーワード: scaffold protein, psychiatric disorder, coiled coil, structural protein
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14565.50

構造登録者

Ye, F.,Yu, C.,Zhang, M. (登録日: 2018-11-14, 公開日: 2019-09-25, 最終更新日: 2024-05-15)

• 主引用文献: Wang, X.,Ye, F.,Wen, Z.,Guo, Z.,Yu, C.,Huang, W.K.,Rojas Ringeling, F.,Su, Y.,Zheng, W.,Zhou, G.,Christian, K.M.,Song, H.,Zhang, M.,Ming, G.L.; Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders.; Mol. Psychiatry, 2019; PubMed: 31444471; DOI: 10.1038/s41380-019-0485-2

実験手法

SOLUTION NMR