6INL
Crystal structure of CDK2 IN complex with Inhibitor CVT-313
Summary for 6INL
| Entry DOI | 10.2210/pdb6inl/pdb |
| Descriptor | Cyclin-dependent kinase 2, 2,2'-{[6-{[(4-methoxyphenyl)methyl]amino}-9-(propan-2-yl)-9H-purin-2-yl]azanediyl}di(ethan-1-ol) (3 entities in total) |
| Functional Keywords | cyclin dependent kinases, cdks, cell cycle-inhibitor complex, cell cycle/inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 34464.04 |
| Authors | Talapati, S.R.,Krishnamurthy, N.R. (deposition date: 2018-10-25, release date: 2019-10-30, Last modification date: 2023-11-22) |
| Primary citation | Talapati, S.R.,Nataraj, V.,Pothuganti, M.,Gore, S.,Ramachandra, M.,Antony, T.,More, S.S.,Krishnamurthy, N.R. Structure of cyclin-dependent kinase 2 (CDK2) in complex with the specific and potent inhibitor CVT-313. Acta Crystallogr.,Sect.F, 76:350-356, 2020 Cited by PubMed: 32744246DOI: 10.1107/S2053230X20009243 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report
