6IMX
Crystal structure of V30M mutated transthyretin in complex with 18-Crown-6
Summary for 6IMX
Entry DOI | 10.2210/pdb6imx/pdb |
Descriptor | Transthyretin, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE (3 entities in total) |
Functional Keywords | transthyretin, amyloid, t4-binding protein, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 35213.79 |
Authors | Yokoyama, T.,Kosaka, Y.,Matsumoto, K.,Kitakami, R.,Nabeshima, Y.,Mizuguchi, M. (deposition date: 2018-10-24, release date: 2019-03-13, Last modification date: 2024-03-27) |
Primary citation | Yokoyama, T.,Mizuguchi, M. Crown Ethers as Transthyretin Amyloidogenesis Inhibitors. J. Med. Chem., 62:2076-2082, 2019 Cited by PubMed: 30688456DOI: 10.1021/acs.jmedchem.8b01700 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.602 Å) |
Structure validation
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