6IIY
Crystal structure of deacetylase triple mutant (Orf2*T) that involving in teicoplanin biosynthetic pathway
Summary for 6IIY
Entry DOI | 10.2210/pdb6iiy/pdb |
Descriptor | deacetylase, IMIDAZOLE, COBALT (II) ION, ... (4 entities in total) |
Functional Keywords | antibiotics, oxidoreductase |
Biological source | Actinoplanes teichomyceticus |
Total number of polymer chains | 1 |
Total formula weight | 32378.78 |
Authors | Li, T.L.,Huang, C.M. (deposition date: 2018-10-08, release date: 2019-10-09, Last modification date: 2023-11-22) |
Primary citation | Huang, C.M.,Lyu, S.Y.,Lin, K.H.,Chen, C.L.,Chen, M.H.,Shih, H.W.,Hsu, N.S.,Lo, I.W.,Wang, Y.L.,Li, Y.S.,Wu, C.J.,Li, T.L. Teicoplanin Reprogrammed with the N-Acyl-Glucosamine Pharmacophore at the Penultimate Residue of Aglycone Acquires Broad-Spectrum Antimicrobial Activities Effectively Killing Gram-Positive and -Negative Pathogens. Acs Infect Dis., 5:430-442, 2019 Cited by PubMed: 30599088DOI: 10.1021/acsinfecdis.8b00317 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.29 Å) |
Structure validation
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