6II4

Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4A-14

Summary for 6II4

• Entry DOI: 10.2210/pdb6ii4/pdb
• Descriptor: Hemagglutinin, Heavy chain of L4A-14 Fab, Light chain of L4A-14 Fab, ... (4 entities in total)
• Functional Keywords: h7 haemagglutinin, receptor binding site, neutralizing antibody, protection in vivo, immune system
• Biological source: Influenza A virus (A/Anhui/DEWH72-02/2013(H7N9)); More
• Total number of polymer chains: 8
• Total formula weight: 200839.21

Authors

Jiang, H.H.,Shi, Y.,Qi, J.,Gao, G.F. (deposition date: 2018-10-03, release date: 2018-10-24, Last modification date: 2019-02-06)

• Primary citation: Huang, K.A.,Rijal, P.,Jiang, H.,Wang, B.,Schimanski, L.,Dong, T.,Liu, Y.M.,Chang, P.,Iqbal, M.,Wang, M.C.,Chen, Z.,Song, R.,Huang, C.C.,Yang, J.H.,Qi, J.,Lin, T.Y.,Li, A.,Powell, T.J.,Jan, J.T.,Ma, C.,Gao, G.F.,Shi, Y.,Townsend, A.R.; Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans.; Nat Microbiol, 4:306-315, 2019; PubMed: 30478290; DOI: 10.1038/s41564-018-0303-7

Experimental method

X-RAY DIFFRACTION (3.3 Å)