6IH5

Crystal structure of Phosphite Dehydrogenase mutant I151R/P176E from Ralstonia sp. 4506 in complex with non-natural cofactor Nicotinamide Cytosine dinucleotide

6IH5 の概要

分子名称Phosphite dehydrogenase, [[(2S,3S,4R,5S)-5-(3-aminocarbonylpyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2S,3S,4R,5S)-5-(4-azanyl-2-oxidanylidene-pyrimidin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate (3 entities in total)
機能のキーワードphosphite dehydrogenase, oxidoreductase
由来する生物種Ralstonia sp. 4506
ポリマー鎖数2
分子量合計74531.88
構造登録者
Song, X.,Feng, Y.,Liu, Y.,Zhao, Z. (登録日: 2018-09-28, 公開日: 2019-03-13)
主引用文献
Liu, Y.,Feng, Y.,Wang, L.,Guo, X.,Liu, W.,Li, Q.,Wang, X.,Xue, S.,Zhao, Z.
Structural Insights into Phosphite Dehydrogenase Variants Favoring a Non-natural Redox Cofactor
Acs Catalysis, 9:1883-1887, 2019
DOI: 10.1021/acscatal.8b04822
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.468 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2568 0.5% 3.0% 6.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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