6ICG

Grb2 SH2 domain in phosphopeptide free form

Summary for 6ICG

DescriptorGrowth factor receptor-bound protein 2, SULFATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywordssrc homology 2 domain, phosphorylated tyrosine, adapter protein, signaling protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight22569.22
Authors
Hosoe, Y.,Numoto, N.,Inaba, S.,Ogawa, S.,Morii, H.,Abe, R.,Ito, N.,Oda, M. (deposition date: 2018-09-06, release date: 2019-07-17)
Primary citation
Hosoe, Y.,Numoto, N.,Inaba, S.,Ogawa, S.,Morii, H.,Abe, R.,Ito, N.,Oda, M.
Structural and functional properties of Grb2 SH2 dimer in CD28 binding.
Biophys Physicobio., 16:80-88, 2019
PubMed: 30923665 (PDB entries with the same primary citation)
DOI: 10.2142/biophysico.16.0_80
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.15 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.16930 0.6% 1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution