6IBO
Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability
Summary for 6IBO
Entry DOI | 10.2210/pdb6ibo/pdb |
Descriptor | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, ALA-VAL-SER-ARG-ALA, (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, ... (5 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 82735.09 |
Authors | Gundogdu, M.,van Aalten, D.M.F. (deposition date: 2018-11-30, release date: 2019-07-24, Last modification date: 2024-01-24) |
Primary citation | Pravata, V.M.,Muha, V.,Gundogdu, M.,Ferenbach, A.T.,Kakade, P.S.,Vandadi, V.,Wilmes, A.C.,Borodkin, V.S.,Joss, S.,Stavridis, M.P.,van Aalten, D.M.F. Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability. Proc.Natl.Acad.Sci.USA, 116:14961-14970, 2019 Cited by PubMed: 31296563DOI: 10.1073/pnas.1900065116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.17 Å) |
Structure validation
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