6IAM

Modulating Protein-Protein Interactions with Visible Light Peptide Backbone Switches

6IAM の概要

• エントリーDOI: 10.2210/pdb6iam/pdb
• 分子名称: WD repeat-containing protein 5, SER-ALA-ARG-ALA-XY5-VAL-HIS-LEU-ARG-LYS-SER-ALA, Small ubiquitin-related modifier 5, ... (6 entities in total)
• 機能のキーワード: histone modification, trimethylation at 'lys-4', epigenetic transcriptional activation, nsl complex, osteoblasts differentiation, leukemia, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 35759.73

構造登録者

Werel, L.,Essen, L.-O. (登録日: 2018-11-27, 公開日: 2019-02-06, 最終更新日: 2023-11-15)

• 主引用文献: Albert, L.,Penalver, A.,Djokovic, N.,Werel, L.,Hoffarth, M.,Ruzic, D.,Xu, J.,Essen, L.O.,Nikolic, K.,Dou, Y.,Vazquez, O.; Modulating Protein-Protein Interactions with Visible-Light-Responsive Peptide Backbone Photoswitches.; Chembiochem, 20:1417-1429, 2019; PubMed: 30675988; DOI: 10.1002/cbic.201800737

実験手法

X-RAY DIFFRACTION (1.51 Å)