6I9B

NMR structure of the La module from human LARP4A

6I9B の概要

• エントリーDOI: 10.2210/pdb6i9b/pdb
• NMR情報: BMRB: 27666
• 分子名称: La-related protein 4 (1 entity in total)
• 機能のキーワード: la-related proteins, larps, pabp-binding protein, la module, rna binding protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20576.67

構造登録者

Conte, M.R.,Martino, L.,Atkinson, R.A.,Kelly, G.,Cruz-Gallardo, I.,De Tito, S.,Trotta, R. (登録日: 2018-11-22, 公開日: 2019-03-13, 最終更新日: 2024-06-19)

• 主引用文献: Cruz-Gallardo, I.,Martino, L.,Kelly, G.,Atkinson, R.A.,Trotta, R.,De Tito, S.,Coleman, P.,Ahdash, Z.,Gu, Y.,Bui, T.T.T.,Conte, M.R.; LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.; Nucleic Acids Res., 47:4272-4291, 2019; PubMed: 30820564; DOI: 10.1093/nar/gkz144

実験手法

SOLUTION NMR