6I8N

Crystal structure of LmrR with V15 replaced by unnatural amino acid 4-amino-L-phenylalanine

6I8N の概要

• エントリーDOI: 10.2210/pdb6i8n/pdb
• 分子名称: Transcriptional regulator, PadR-like family, 3[N-MORPHOLINO]PROPANE SULFONIC ACID (3 entities in total)
• 機能のキーワード: padr family, transcriptional regulator, engineered variant, artificial enzyme, unnatural amino acid, dna binding protein
• 由来する生物種: Lactococcus lactis subsp. cremoris (strain MG1363)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29864.95

構造登録者

Reddem, R.,Thunnissen, A.M.W.H. (登録日: 2018-11-20, 公開日: 2019-01-02, 最終更新日: 2024-01-24)

• 主引用文献: Mayer, C.,Dulson, C.,Reddem, E.,Thunnissen, A.W.H.,Roelfes, G.; Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid.; Angew. Chem. Int. Ed. Engl., 58:2083-2087, 2019; PubMed: 30575260; DOI: 10.1002/anie.201813499

実験手法

X-RAY DIFFRACTION (1.79 Å)