6I3D

Crystal structure of Human soluble catechol O-methyltransferase in complex with 3,5-dinitrocatechol and Sinefungin

6I3D の概要

• エントリーDOI: 10.2210/pdb6i3d/pdb
• 分子名称: Catechol O-methyltransferase, 3,5-DINITROCATECHOL, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: enzyme, s-adenosyl-l-methionine, catechol o-methyltransferase, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53152.83

構造登録者

Levy, C.W. (登録日: 2018-11-05, 公開日: 2019-09-18, 最終更新日: 2024-05-01)

• 主引用文献: Czarnota, S.,Johannissen, L.O.,Baxter, N.J.,Rummel, F.,Wilson, A.L.,Cliff, M.J.,Levy, C.W.,Scrutton, N.S.,Waltho, J.P.,Hay, S.; Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase.; Acs Catalysis, 9:4394-4401, 2019; PubMed: 31080692; DOI: 10.1021/acscatal.9b00174

実験手法

X-RAY DIFFRACTION (1.45 Å)