6I2U

Aurora-A kinase domain in complex with Coenzyme A

Summary for 6I2U

Entry DOI	10.2210/pdb6i2u/pdb
Descriptor	Aurora kinase A, COENZYME A, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	aurora a coenzyme a kinase covalent, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	34291.86
Authors	Burgess, S.G.,Bayliss, R. (deposition date: 2018-11-02, release date: 2019-10-02, Last modification date: 2024-01-24)
Primary citation	Tsuchiya, Y.,Byrne, D.P.,Burgess, S.G.,Bormann, J.,Bakovic, J.,Huang, Y.,Zhyvoloup, A.,Yu, B.Y.K.,Peak-Chew, S.,Tran, T.,Bellany, F.,Tabor, A.B.,Chan, A.E.,Guruprasad, L.,Garifulin, O.,Filonenko, V.,Vonderach, M.,Ferries, S.,Eyers, C.E.,Carroll, J.,Skehel, M.,Bayliss, R.,Eyers, P.A.,Gout, I. Covalent Aurora A regulation by the metabolic integrator coenzyme A. Redox Biol, 28:101318-101318, 2019 Cited by PubMed: 31546169 DOI: 10.1016/j.redox.2019.101318 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation